Cogan syndrome

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Cogan syndrome is a rare disorder characterized by recurrent inflammation of the front of the eye (the cornea) and often fever, fatigue, and weight loss, episodes of dizziness, and hearing loss. It can lead to deafness or blindness if untreated. The classic form of the disease was first described by D.G. Cogan in 1945.

Contents 1 Symptoms 2 History 3 Related disorders 4 References

[edit] Symptoms

Symptoms of Cogan's Syndrome include a decrease in vision (typically in one eye) and either a decrease in hearing or a "ringing" sensation in the same ear. Treatment includes steroids (most commonly prednisone) to address inflammation.

[edit] History

In 1945 D.G. Cogan first described the "nonsyphilitic interstitial keratitis and vestibuloauditory symptoms" that would later bear his name (Cogan, 1945). In 1963, the atypical form of Cogan syndrome was first described (Bennett, 1963)

[edit] Related disorders

• McCabe disease

[edit] References

• Cogan DG (1945). "Syndrome of nonsyphilitic interstitial keratitis and vestiboloauditory symptoms". Arch Ophthalmol 33: 144–9. 

• Bennett FM (1963). "Bilateral recurrent episcleritis associated with posterior corneal changes, vestibulo-auditory symptoms and rheumatoid arthritis". Am J Ophthalmol 55: 815–8.  PMID 13967466