COG3

From Wikipedia, the free encyclopedia


Component of oligomeric golgi complex 3
Identifiers
Symbol(s) COG3; SEC34
External IDs OMIM: 606975 MGI: 2450151 HomoloGene: 5854
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 83548 338337
Ensembl ENSG00000136152 ENSMUSG00000034893
Uniprot Q96JB2 Q3USH9
Refseq NM_031431 (mRNA)
NP_113619 (protein)		 NM_177381 (mRNA)
NP_796355 (protein)
Location Chr 13: 44.94 - 45.01 Mb Chr 14: 74.44 - 74.49 Mb
Pubmed search [1] [2]

Component of oligomeric golgi complex 3, also known as COG3, is a human gene.[1]

The protein encoded by this gene has similarity to a yeast protein. It seems to be part of a peripheral membrane protein complex localized on cis/medial Golgi cisternae where it may participate in tethering intra-Golgi transport vesicles.[1]

[edit] References

  1. ^ a b Entrez Gene: COG3 component of oligomeric golgi complex 3.

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298. 
  • Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107-13. doi:10.1006/abio.1996.0138. PMID 8619474. 
  • Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353-8. PMID 9110174. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149. 
  • Kim DW, Sacher M, Scarpa A, et al. (1999). "High-copy suppressor analysis reveals a physical interaction between Sec34p and Sec35p, a protein implicated in vesicle docking.". Mol. Biol. Cell 10 (10): 3317-29. PMID 10512869. 
  • VanRheenen SM, Cao X, Sapperstein SK, et al. (1999). "Sec34p, a protein required for vesicle tethering to the yeast Golgi apparatus, is in a complex with Sec35p.". J. Cell Biol. 147 (4): 729-42. PMID 10562277. 
  • Suvorova ES, Kurten RC, Lupashin VV (2001). "Identification of a human orthologue of Sec34p as a component of the cis-Golgi vesicle tethering machinery.". J. Biol. Chem. 276 (25): 22810-8. doi:10.1074/jbc.M011624200. PMID 11292827. 
  • Loh E, Hong W (2002). "Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp.". J. Biol. Chem. 277 (24): 21955-61. doi:10.1074/jbc.M202326200. PMID 11929878. 
  • Ungar D, Oka T, Brittle EE, et al. (2002). "Characterization of a mammalian Golgi-localized protein complex, COG, that is required for normal Golgi morphology and function.". J. Cell Biol. 157 (3): 405-15. doi:10.1083/jcb.200202016. PMID 11980916. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.". Nat. Biotechnol. 21 (5): 566-9. doi:10.1038/nbt810. PMID 12665801. 
  • Loh E, Hong W (2004). "The binary interacting network of the conserved oligomeric Golgi tethering complex.". J. Biol. Chem. 279 (23): 24640-8. doi:10.1074/jbc.M400662200. PMID 15047703. 
  • Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature 428 (6982): 522-8. doi:10.1038/nature02379. PMID 15057823. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
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