Talk:Clindamycin

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	Clindamycin has been listed as one of the Natural sciences good articles under the good article criteria. If you can improve it further, please do. If it no longer meets these criteria, you can delist it, or ask for a reassessment.
December 15, 2007 Good article nominee Listed

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GA	This article has been rated as GA-Class on the quality scale.
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..what is a penal cap? —This unsigned comment was added by Seyon (talk • contribs) .

...good question. Ask this guy, he put it there. —Keenan Pepper 03:33, 22 March 2006 (UTC)

[edit] Acne

"However, Clindamycin is rarely effective alone when treating acne. Studies have shown it to be most effective when used in conjunction with benzoyl peroxide."

Is there a source for this statement? I ask because it runs contrary to what I have heard elsewhere. Not that this makes it false obviously, but it seems there should at least be a footnote or something, or remove the statement if nobody knows where its from. 15:47, 1 November 2007 (UTC)

Since reworded, with appropriate citations. Fvasconcellos (t·c) 22:53, 7 December 2007 (UTC)

[edit] GA nom

I'll do a review for GA in the next few days. Jimfbleak (talk) 07:47, 14 December 2007 (UTC)

Thanks! Fvasconcellos (t·c) 12:24, 14 December 2007 (UTC)

First quick read through:

1. I tweaked a couple of places and added a missing ")"

   Thanks; I don't really get the point of this parenthesis, though? Fvasconcellos (t·c) 12:24, 14 December 2007 (UTC)

2. Main first-thoughts issue: "Mechanism of action" and "Interactions" are very short sections which largely repeat each other: compare in a similar way to erythromycin, azithromycin and chloramphenicol, by binding to the 50S subunit of the bacterial ribosome. This causes antagonism if administered simultaneously with those drugs, and possible cross-resistance. with Its similarity to the mechanism of action of macrolides and chloramphenicol means they should not be given simultaneously, as this causes antagonism and possible cross-resistance. The duplication needs to go, but that would make one of the sections too short - can they be rolled up or reorganised?

   Yes, I noticed that (the duplication). I'll reword the "Interactions" section; it will get shorter, but there really aren't that many clinically relevant interactions of clindamycin to begin with AFAIK. Fvasconcellos (t·c) 12:24, 14 December 2007 (UTC)

   I've gone the other way round (more logical): kept that info in the "Interactions" section and removed it from "Mechanism of action". I've also added a note on study of the complex between clindamycin and the ribosome, and the fact that a crystal structure of the complex has been published. Fvasconcellos (t·c) 23:47, 14 December 2007 (UTC)

3. Is there a photo of the product available? (not essential)

   I don't think so. Fvasconcellos (t·c) 12:24, 14 December 2007 (UTC)

Jimfbleak (talk) 08:29, 14 December 2007 (UTC)

[edit] Good Article nomination

GA review (see here for criteria)

1. It is reasonably well written.

   a (prose): b (MoS):

2. It is factually accurate and verifiable.

   a (references): b (citations to reliable sources): c (OR):

3. It is broad in its coverage.

   a (major aspects): b (focused):

4. It follows the neutral point of view policy.

   Fair representation without bias:

5. It is stable.

   No edit wars etc.:

6. It is illustrated by images, where possible and appropriate.

   a (images are tagged and non-free images have fair use rationales): b (appropriate use with suitable captions):

7. Overall:

   Pass/Fail:

I've made a few minor tweaks, can't see anything else, so PASS Jimfbleak (talk) 13:51, 15 December 2007 (UTC)