Clevidipine

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Clevidipine
Systematic (IUPAC) name
O3-(butanoyloxymethyl) O5-methyl (4R)- 4-(2,3-dichlorophenyl)-2,6-dimethyl- 1,4-dihydropyridine-3,5-dicarboxylate
Identifiers
CAS number 166432-28-6
ATC code  ?
PubChem 193993
Chemical data
Formula C21H23Cl2NO6 
Mol. mass 456.316 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes Intravenous

Clevidipine (INN; planned trade name Cleviprex) is an ultra short-acting[1] calcium channel blocker which is currently under regulatory review by the United States Food and Drug Administration for the treatment of acute severe hypertension.

[edit] References

  1. ^ Gradman AH, Vivas Y. New therapeutic perspectives with clevidipine: an ultra-short-acting intravenous Ca2+ channel blocker. Expert Opin Investig Drugs 2007;9:1449-57. PMID 17714030.