CLDN12

From Wikipedia, the free encyclopedia

Claudin 12

Identifiers

External IDs

MGI: 1929288 HomoloGene: 40809

Gene ontology
Molecular Function:	• structural molecule activity • identical protein binding
Cellular Component:	• tight junction • membrane • integral to membrane
Biological Process:	• calcium-independent cell-cell adhesion

Orthologs

Human

Mouse

Refseq

NM_012129 (mRNA)
NP_036261 (protein)

NM_022890 (mRNA)
NP_075028 (protein)

Location

Chr 7: 89.87 - 89.88 Mb

Chr 5: 5.51 - 5.52 Mb

Pubmed search

[1]

[2]

Claudin 12, also known as CLDN12, is a human gene.^[1] It belongs to the group of claudins.

[edit] References

^ Entrez Gene: CLDN12 claudin 12.

[edit] Further reading

Kniesel U, Wolburg H (2000). "Tight junctions of the blood-brain barrier.". Cell. Mol. Neurobiol. 20 (1): 57-76. PMID 10690502.
Heiskala M, Peterson PA, Yang Y (2001). "The roles of claudin superfamily proteins in paracellular transport.". Traffic 2 (2): 93-8. PMID 11247307.
Tsukita S, Furuse M, Itoh M (2001). "Multifunctional strands in tight junctions.". Nat. Rev. Mol. Cell Biol. 2 (4): 285-93. doi:10.1038/35067088. PMID 11283726.
Tsukita S, Furuse M (2003). "Claudin-based barrier in simple and stratified cellular sheets.". Curr. Opin. Cell Biol. 14 (5): 531-6. PMID 12231346.
González-Mariscal L, Betanzos A, Nava P, Jaramillo BE (2003). "Tight junction proteins.". Prog. Biophys. Mol. Biol. 81 (1): 1-44. PMID 12475568.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788-95. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422-35. doi:10.1101/gr.154701. PMID 11230166.
Niimi T, Nagashima K, Ward JM, et al. (2001). "claudin-18, a novel downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor, encodes lung- and stomach-specific isoforms through alternative splicing.". Mol. Cell. Biol. 21 (21): 7380-90. doi:10.1128/MCB.21.21.7380-7390.2001. PMID 11585919.
Kiuchi-Saishin Y, Gotoh S, Furuse M, et al. (2002). "Differential expression patterns of claudins, tight junction membrane proteins, in mouse nephron segments.". J. Am. Soc. Nephrol. 13 (4): 875-86. PMID 11912246.
Brandner JM, Kief S, Grund C, et al. (2003). "Organization and formation of the tight junction system in human epidermis and cultured keratinocytes.". Eur. J. Cell Biol. 81 (5): 253-63. PMID 12067061.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767-72. doi:10.1126/science.1083423. PMID 12690205.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7.". Nature 424 (6945): 157-64. doi:10.1038/nature01782. PMID 12853948.
Kitajiri SI, Furuse M, Morita K, et al. (2004). "Expression patterns of claudins, tight junction adhesion molecules, in the inner ear.". Hear. Res. 187 (1-2): 25-34. PMID 14698084.
Acharya P, Beckel J, Ruiz WG, et al. (2004). "Distribution of the tight junction proteins ZO-1, occludin, and claudin-4, -8, and -12 in bladder epithelium.". Am. J. Physiol. Renal Physiol. 287 (2): F305-18. doi:10.1152/ajprenal.00341.2003. PMID 15068973.