Cis-dihydroethylcatechol dehydrogenase

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In enzymology, a cis-dihydroethylcatechol dehydrogenase (EC 1.3.1.66) is an enzyme that catalyzes the chemical reaction

cis-1,2-dihydro-3-ethylcatechol + NAD⁺ 3-ethylcatechol + NADH + H⁺

Thus, the two substrates of this enzyme are cis-1,2-dihydro-3-ethylcatechol and NAD⁺, whereas its 3 products are 3-ethylcatechol, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-1,2-dihydro-3-ethylcatechol:NAD+ oxidoreductase. This enzyme participates in ethylbenzene degradation.

[edit] References

• IUBMB entry for 1.3.1.66
• BRENDA references for 1.3.1.66 (Recommended.)
• PubMed references for 1.3.1.66
• PubMed Central references for 1.3.1.66
• Google Scholar references for 1.3.1.66
• Gibson DT, Gschwendt B, Yeh WK, Kobal VM (1973). "Initial reactions in the oxidation of ethylbenzene by Pseudomonas putida". Biochemistry. 12: 1520–8. doi:10.1021/bi00732a008. PMID 4699984. 

[edit] External links

• IUBMB entry for 1.3.1.66

• KEGG entry for 1.3.1.66

• BRENDA entry for 1.3.1.66

• NiceZyme view of 1.3.1.66

• EC2PDB: PDB structures for 1.3.1.66

• PRIAM entry for 1.3.1.66

• PUMA2 entry for 1.3.1.66

• IntEnz: Integrated Enzyme entry for 1.3.1.66

• MetaCyc entry for 1.3.1.66

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018519: cis-dihydroethylcatechol dehydrogenase

• AMIGO entry for GO code 0018519: cis-dihydroethylcatechol dehydrogenase