Cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase

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In enzymology, a cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase (EC 1.3.1.49) is an enzyme that catalyzes the chemical reaction

(+)-cis-3,4-dihydrophenanthrene-3,4-diol + NAD⁺ phenanthrene-3,4-diol + NADH + H⁺

Thus, the two substrates of this enzyme are (+)-cis-3,4-dihydrophenanthrene-3,4-diol and NAD⁺, whereas its 3 products are phenanthrene-3,4-diol, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (+)-cis-3,4-dihydrophenanthrene-3,4-diol:NAD+ 3,4-oxidoreductase. This enzyme participates in naphthalene and anthracene degradation.

[edit] References

• IUBMB entry for 1.3.1.49
• BRENDA references for 1.3.1.49 (Recommended.)
• PubMed references for 1.3.1.49
• PubMed Central references for 1.3.1.49
• Google Scholar references for 1.3.1.49
• Nagao K, Takizawa N and Kiyahara H (1988). "Purification and properties of cis-phenanthrene dihydrodiol dehydrogenase in Alcaligenes faecalis AFK2". Agric. Biol. Chem. 52: 2621–2623. 

[edit] External links

The CAS registry number for this enzyme class is 118390-61-7.

• IUBMB entry for 1.3.1.49

• KEGG entry for 1.3.1.49

• BRENDA entry for 1.3.1.49

• NiceZyme view of 1.3.1.49

• EC2PDB: PDB structures for 1.3.1.49

• PRIAM entry for 1.3.1.49

• PUMA2 entry for 1.3.1.49

• IntEnz: Integrated Enzyme entry for 1.3.1.49

• MetaCyc entry for 1.3.1.49

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018507: cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase

• AMIGO entry for GO code 0018507: cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase