Cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase (EC 1.3.1.29) is an enzyme that catalyzes the chemical reaction

cis-1,2-dihydronaphthalene-1,2-diol + NAD⁺ naphthalene-1,2-diol + NADH + H⁺

Thus, the two substrates of this enzyme are cis-1,2-dihydronaphthalene-1,2-diol and NAD⁺, whereas its 3 products are naphthalene-1,2-diol, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-1,2-dihydronaphthalene-1,2-diol:NAD+ 1,2-oxidoreductase. Other names in common use include (+)-cis-naphthalene dihydrodiol dehydrogenase, naphthalene dihydrodiol dehydrogenase, and cis-dihydrodiol naphthalene dehydrogenase. This enzyme participates in 1- and 2-methylnaphthalene degradation and naphthalene and anthracene degradation.

[edit] References

• IUBMB entry for 1.3.1.29
• BRENDA references for 1.3.1.29 (Recommended.)
• PubMed references for 1.3.1.29
• PubMed Central references for 1.3.1.29
• Google Scholar references for 1.3.1.29
• Patel TR, Gibson DT (1974). "Purification and propeties of (plus)-cis-naphthalene dihydrodiol dehydrogenase of Pseudomonas putida". J. Bacteriol. 119: 879–88. PMID 4369091. 

[edit] External links

The CAS registry number for this enzyme class is 53986-49-5.

• IUBMB entry for 1.3.1.29

• KEGG entry for 1.3.1.29

• BRENDA entry for 1.3.1.29

• NiceZyme view of 1.3.1.29

• EC2PDB: PDB structures for 1.3.1.29

• PRIAM entry for 1.3.1.29

• PUMA2 entry for 1.3.1.29

• IntEnz: Integrated Enzyme entry for 1.3.1.29

• MetaCyc entry for 1.3.1.29

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018505: cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase

• AMIGO entry for GO code 0018505: cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase