CIDEB

From Wikipedia, the free encyclopedia

Cell death-inducing DFFA-like effector b

PDB rendering based on 1d4b.

Available structures: 1d4b

Identifiers

Symbol(s)

CIDEB;

External IDs

OMIM: 604441 MGI: 1270844 HomoloGene: 7666

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• intracellular • cytosol
Biological Process:	• apoptosis • induction of apoptosis • DNA damage response, signal transduction resulting in induction of apoptosis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_014430 (mRNA)
NP_055245 (protein)

NM_009894 (mRNA)
NP_034024 (protein)

Location

Chr 14: 23.84 - 23.85 Mb

Chr 14: 54.71 - 54.71 Mb

Pubmed search

[1]

[2]

Cell death-inducing DFFA-like effector b, also known as CIDEB, is a human gene.^[1]

[edit] References

^ Entrez Gene: CIDEB cell death-inducing DFFA-like effector b.

[edit] Further reading

Inohara N, Koseki T, Chen S, et al. (1998). "CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor.". EMBO J. 17 (9): 2526-33. doi:10.1093/emboj/17.9.2526. PMID 9564035.
Lugovskoy AA, Zhou P, Chou JJ, et al. (2000). "Solution structure of the CIDE-N domain of CIDE-B and a model for CIDE-N/CIDE-N interactions in the DNA fragmentation pathway of apoptosis.". Cell 99 (7): 747-55. PMID 10619428.
Chen Z, Guo K, Toh SY, et al. (2000). "Mitochondria localization and dimerization are required for CIDE-B to induce apoptosis.". J. Biol. Chem. 275 (30): 22619-22. doi:10.1074/jbc.C000207200. PMID 10837461.
Liang L, Zhao M, Xu Z, et al. (2003). "Molecular cloning and characterization of CIDE-3, a novel member of the cell-death-inducing DNA-fragmentation-factor (DFF45)-like effector family.". Biochem. J. 370 (Pt 1): 195-203. doi:10.1042/BJ20020656. PMID 12429024.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Erdtmann L, Franck N, Lerat H, et al. (2003). "The hepatitis C virus NS2 protein is an inhibitor of CIDE-B-induced apoptosis.". J. Biol. Chem. 278 (20): 18256-64. doi:10.1074/jbc.M209732200. PMID 12595532.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Da L, Li D, Yokoyama KK, et al. (2006). "Dual promoters control the cell-specific expression of the human cell death-inducing DFF45-like effector B gene.". Biochem. J. 393 (Pt 3): 779-88. doi:10.1042/BJ20051027. PMID 16248853.