CHST14

From Wikipedia, the free encyclopedia

Dermatan 4 sulfotransferase 1

Identifiers

D4ST1; HNK1ST; D4ST-1; HD4ST

External IDs

MGI: 1919386 HomoloGene: 12443

Gene ontology
Molecular Function:	• N-acetylgalactosamine 4-O-sulfotransferase activity • protein binding • transferase activity • phosphate binding
Cellular Component:	• membrane • integral to membrane
Biological Process:	• carbohydrate metabolic process • dermatan sulfate proteoglycan metabolic process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_130468 (mRNA)
NP_569735 (protein)

NM_028117 (mRNA)
NP_082393 (protein)

Location

Chr 15: 38.55 - 38.55 Mb

Chr 2: 118.62 - 118.62 Mb

Pubmed search

[1]

[2]

Dermatan 4 sulfotransferase 1, also known as D4ST1, is a human gene.^[1]

[edit] References

^ Entrez Gene: D4ST1 dermatan 4 sulfotransferase 1.

[edit] Further reading

Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117-26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309.
Mikami T, Mizumoto S, Kago N, et al. (2003). "Specificities of three distinct human chondroitin/dermatan N-acetylgalactosamine 4-O-sulfotransferases demonstrated using partially desulfated dermatan sulfate as an acceptor: implication of differential roles in dermatan sulfate biosynthesis.". J. Biol. Chem. 278 (38): 36115-27. doi:10.1074/jbc.M306044200. PMID 12847091.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Evers MR, Xia G, Kang HG, et al. (2001). "Molecular cloning and characterization of a dermatan-specific N-acetylgalactosamine 4-O-sulfotransferase.". J. Biol. Chem. 276 (39): 36344-53. doi:10.1074/jbc.M105848200. PMID 11470797.