CHST12

From Wikipedia, the free encyclopedia

Carbohydrate (chondroitin 4) sulfotransferase 12

Identifiers

CHST12; C4S-2; C4ST-2; C4ST2

External IDs

OMIM: 610129 MGI: 1929064 HomoloGene: 69258

Gene ontology
Molecular Function:	• transferase activity • chondroitin 4-sulfotransferase activity • 3'-phosphoadenosine 5'-phosphosulfate binding
Cellular Component:	• membrane • integral to membrane • integral to Golgi membrane
Biological Process:	• carbohydrate metabolic process • dermatan sulfate biosynthetic process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_018641 (mRNA)
NP_061111 (protein)

NM_021528 (mRNA)
NP_067503 (protein)

Location

Chr 7: 2.41 - 2.44 Mb

Chr 5: 140.76 - 140.78 Mb

Pubmed search

[1]

[2]

Carbohydrate (chondroitin 4) sulfotransferase 12, also known as CHST12, is a human gene.^[1]

[edit] References

^ Entrez Gene: CHST12 carbohydrate (chondroitin 4) sulfotransferase 12.

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Hiraoka N, Nakagawa H, Ong E, et al. (2000). "Molecular cloning and expression of two distinct human chondroitin 4-O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family.". J. Biol. Chem. 275 (26): 20188–96. doi:10.1074/jbc.M002443200. PMID 10781601.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767–72. doi:10.1126/science.1083423. PMID 12690205.
Mikami T, Mizumoto S, Kago N, et al. (2003). "Specificities of three distinct human chondroitin/dermatan N-acetylgalactosamine 4-O-sulfotransferases demonstrated using partially desulfated dermatan sulfate as an acceptor: implication of differential roles in dermatan sulfate biosynthesis.". J. Biol. Chem. 278 (38): 36115–27. doi:10.1074/jbc.M306044200. PMID 12847091.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.