CHST11

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Carbohydrate (chondroitin 4) sulfotransferase 11

Identifiers

Symbol(s)

CHST11; C4ST; C4ST-1; C4ST1; HSA269537

External IDs

OMIM: 610128 MGI: 1927166 HomoloGene: 56808

Gene ontology
Molecular Function:	• N-acetylgalactosamine 4-O-sulfotransferase activity • transferase activity • chondroitin 4-sulfotransferase activity
Cellular Component:	• membrane • integral to membrane
Biological Process:	• carbohydrate metabolic process • chondroitin sulfate biosynthetic process

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_018413 (mRNA)
NP_060883 (protein)

NM_021439 (mRNA)
NP_067414 (protein)

Location

Chr 12: 103.37 - 103.68 Mb

Chr 10: 82.42 - 82.63 Mb

Pubmed search

[1]

[2]

Carbohydrate (chondroitin 4) sulfotransferase 11, also known as CHST11, is a human gene.^[1]

[edit] References

^ Entrez Gene: CHST11 carbohydrate (chondroitin 4) sulfotransferase 11.

[edit] Further reading

Yamauchi S, Mita S, Matsubara T, et al. (2000). "Molecular cloning and expression of chondroitin 4-sulfotransferase.". J. Biol. Chem. 275 (12): 8975-81. PMID 10722746.
Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491-6. PMID 10737800.
Hiraoka N, Nakagawa H, Ong E, et al. (2000). "Molecular cloning and expression of two distinct human chondroitin 4-O-sulfotransferases that belong to the HNK-1 sulfotransferase gene family.". J. Biol. Chem. 275 (26): 20188-96. doi:10.1074/jbc.M002443200. PMID 10781601.
Okuda T, Mita S, Yamauchi S, et al. (2001). "Molecular cloning, expression, and chromosomal mapping of human chondroitin 4-sulfotransferase, whose expression pattern in human tissues is different from that of chondroitin 6-sulfotransferase.". J. Biochem. 128 (5): 763-70. PMID 11056388.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Mikami T, Mizumoto S, Kago N, et al. (2003). "Specificities of three distinct human chondroitin/dermatan N-acetylgalactosamine 4-O-sulfotransferases demonstrated using partially desulfated dermatan sulfate as an acceptor: implication of differential roles in dermatan sulfate biosynthesis.". J. Biol. Chem. 278 (38): 36115-27. doi:10.1074/jbc.M306044200. PMID 12847091.
Schmidt HH, Dyomin VG, Palanisamy N, et al. (2004). "Deregulation of the carbohydrate (chondroitin 4) sulfotransferase 11 (CHST11) gene in a B-cell chronic lymphocytic leukemia with a t(12;14)(q23;q32).". Oncogene 23 (41): 6991-6. doi:10.1038/sj.onc.1207934. PMID 15273723.
Yamada T, Ohtake S, Sato M, Habuchi O (2005). "Chondroitin 4-sulphotransferase-1 and chondroitin 6-sulphotransferase-1 are affected differently by uronic acid residues neighbouring the acceptor GalNAc residues.". Biochem. J. 384 (Pt 3): 567-75. doi:10.1042/BJ20040965. PMID 15324304.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Yusa A, Kitajima K, Habuchi O. "N-linked oligosaccharides are required to produce and stabilize the active form of chondroitin 4-sulphotransferase-1.". Biochem. J. 388 (Pt 1): 115-21. doi:10.1042/BJ20041573. PMID 15628971.