Talk:Chronic prostatitis/chronic pelvic pain syndrome

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[edit] Major new overview study published in top journal

The Journal of Urology (known as "the white journal" by urologists since it is one of the top medical journals in the world) has just published a major new study that looks back over 30 years of research into this field. You can read it here. I think this should be used as a starting point for any further editing of the page. If there is no objection, I shall use it as a reference for a lot of future changes. ► RATEL ◄ 14:38, 28 April 2008 (UTC)

[edit] NIH alfusozin study

Objection to posting findings of the study because not yet published in a journal. This was a large, multi-center, NIH run study whose findings have a direct impact on patient care today. Abstract is published in the Journal of Urology AUA edition. Not reasonable to wait on every bit of medical evidence to go through the 6-12 months it takes to be published in a journal if level of quality (patient numbers, study design, track record of investigators) is strong enough. Is this not more important than a list of famous dead people who may have had prostatitis based on newspaper accounts? I completely agree that minor abstracts should not be given the weight of peer reviewed journal articles and that not all journal articles are of equal weight. I would also support removing the information if no article is forthcoming. Nevertheless, I believe that deleting this edit sets the bar too high, and would call into question some of the other more speculative parts of the CPPS wiki entry. Wlosy (talk) 15:32, 21 May 2008 (UTC)

• Please read rules for reliable sources for medical articles. Thank you and keep contributing. ► RATEL ◄ 15:36, 21 May 2008 (UTC)

Failure of alfusozin does not mean other alpha blockers will fail also. Alfusozin is relatively selective for the alpha1a receptor subtype. Alpha receptors that control pain in the spinal cord may be other subtypes. Note that studies of less selective alpha blockers in CPPS (Cardura, Hytrin) while smaller in numbers, were all positive studies. Wlosy (talk) 22:03, 26 May 2008 (UTC)

Actually, the abstract ends with the conclusion:

This large NIH/NIDDK sponsored multicenter randomized placebo controlled North American trial will provide an evidence based foundation to help physicians decide whether or not to prescribe alpha-blockers for men with newly diagnosed CP/CPPS.

The inference that the study relates to all alpha blockers may justifiably be drawn. However, I see no problem leaving the edit you made, for now.► RATEL ◄ 22:40, 26 May 2008 (UTC)