Talk:Chronic kidney disease

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Newer therapy to stop the progression of diabetic nephropathy are imminent. A protein kinase C beta inhibitor, Ruboxistaurin, may be useful in arresting the progression of diabetic nephropathy and decreasing proteinuria. 71.104.222.228 18:51, 10 February 2006 (UTC)

Should this not go on diabetic nephropathy? JFW | T@lk 23:31, 11 February 2006 (UTC)
I'm not sure. I'm thinking the new evidence implies damage is done due to a hyper reninaemic state potentiated by a nephrotic syndrome.. i.e DN causes greater damage by Hypertensive damage to kidney. Hence ESRD rather than hypoalbumineamia or whatever. In any case I'm not sure that the research for

hard endpoints like ESRD is back for ARBs and that should be taken out of the article until it is cited properly. Markjohndaley 18:54, 7 May 2007 (UTC)

Contents

[edit] Should there be a Feline or Veterinary CRF entry?

I notice that there are links to Feline CRF websites on this page. Should there be a Veterinary entry or a Feline entry separate from this human-oriented one? Things would be very confusing if this entry started talking about Sub-Q and Azodyl, and it's confusing that this entry talks about blood pressure and kidney replacement as well as dialysis since those aren't usual options for cats. I'll be happy to create the page or a subsection of this one. QuickieWiki 00:35, 19 June 2007 (UTC)

I came here to essentially ask the same question. Shinobu 18:24, 22 September 2007 (UTC)

www.kidney.org.uk site states that only 1 in 10 CKD sufferers every progress to the stage of needing a transplant / dialysis. Should this be included ?

[edit] What happened to CKD stage I (or CKD stages at all?)

Proteinuria, in the absence of a declining GFR, is indicative of CKD. Witness the stages of CKD, in which CKD I is described, highlighting patients with evidence of kidney injury, despite an as yet apparent bump in creatinine. —Gaff ταλκ 01:23, 18 October 2007 (UTC)

Comments on the new sections for CKD? and changes form CRF to CKD? and the use of stage 5 CKD rather than other terms including ESRD? There had been discussion prior to making these changes on the talk page Wikipedia talk:WikiProject Nephrology. Cheers, BillpSea 18:03, 21 October 2007 (UTC)

[edit] Epidemiology

www.kidney.org.uk site states that only 1 in 10 CKD sufferers every progress to the stage of needing a transplant / dialysis. Should this be included ? Prevalence in USA JFW | T@lk 07:10, 7 November 2007 (UTC)

I agree that this is a worthy section; I was thinking of another angle on prevalence Kidney trouble speeds up heart disease Those in stage 3 and 4 are far more likely to die of heart problems than progress to stage 5. I know there are better sources out there, I'll try to find one or more.BillpSea 07:45, 7 November 2007 (UTC)

[edit] measurements given

creatinine clearance is the most common measurement used, could an approx value be listed for each stage alongside the other type of measurement?Heby 00:08, 15 November 2007 (UTC)

"Formulaic estimates of clearances can provide better information than serum creatinine alone." Nephrology Dialysis Transplantation letterBillpSea 17:07, 15 November 2007 (UTC)

[edit] Vitamin D

Vitamin D does not consistently decrease PTH. Ouch. JFW | T@lk 14:03, 18 December 2007 (UTC)