Chrysanthemyl diphosphate synthase

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In enzymology, a chrysanthemyl diphosphate synthase (EC 2.5.1.67) is an enzyme that catalyzes the chemical reaction

2 dimethylallyl diphosphate diphosphate + chrysanthemyl diphosphate

Hence, this enzyme has one substrate, dimethylallyl diphosphate, and two products, diphosphate and chrysanthemyl diphosphate.

This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is dimethylallyl-diphosphate:dimethylallyl-diphosphate dimethylallyltransferase (chrysanthemyl-diphosphate-forming). This enzyme is also called CPPase.

[edit] References

• IUBMB entry for 2.5.1.67
• BRENDA references for 2.5.1.67 (Recommended.)
• PubMed references for 2.5.1.67
• PubMed Central references for 2.5.1.67
• Google Scholar references for 2.5.1.67
• Shattuck-Eidens DM, Wrobel WM, Peiser GD, Poulter CD (2001). "Chrysanthemyl diphosphate synthase: isolation of the gene and characterization of the recombinant non-head-to-tail monoterpene synthase from Chrysanthemum cinerariaefolium". Proc. Natl. Acad. Sci. U. S. A. 98: 4373–8. doi:10.1073/pnas.071543598. PMID 11287653. 
• Erickson HK, Poulter CD (2003). "Chrysanthemyl diphosphate synthase. The relationship among chain elongation, branching, and cyclopropanation reactions in the isoprenoid biosynthetic pathway". J. Am. Chem. Soc. 125: 6886–8. doi:10.1021/ja034520g. PMID 12783539. 

[edit] External links

• IUBMB entry for 2.5.1.67

• KEGG entry for 2.5.1.67

• BRENDA entry for 2.5.1.67

• NiceZyme view of 2.5.1.67

• EC2PDB: PDB structures for 2.5.1.67

• PRIAM entry for 2.5.1.67

• PUMA2 entry for 2.5.1.67

• IntEnz: Integrated Enzyme entry for 2.5.1.67

• MetaCyc entry for 2.5.1.67

• Atomic-resolution structures of enzymes belonging to this class