Chronic liver disease
From Wikipedia, the free encyclopedia
Chronic liver disease is a liver disease of slow process and persisting over a long period of time, resulting in a progressive destruction of the liver.
It includes amongst others:
- Cirrhosis of the liver
- Alcoholic liver disease
- Hepatitis
- Liver failure
- Portal hypertension
- Hemochromatosis
- Wilson's disease
- Gaucher disease
- Hepatocellular carcinoma (Liver cancer)
- Hepatoma
- Primary biliary cirrhosis
- Primary sclerosing cholangitis
- Sarcoidosis
- Zellweger syndrome
[edit] Stigmata
Stigmata of chronic liver disease are a group of symptoms found in liver disease, which indicate a superimposed hepatic process.
The typical patient is [1]:
- Icteric (jaundiced)
- Pigmented
- Cyanosed (due to pulmonary venous shunting in the hepatopulmonary syndrome)
Clinical signs include[1]:
- Clubbing
- Leuconychia
- Palmar erythema
- Dupuytren's contracture
- Asterixis [2]
- Spider angiomata [2]
- Scratch marks
- Purpura
- Gynaecomastia
- Scanty body hair
- Testicular atrophy
- Hepatomegaly
- Splenomegaly
- Ascites [2]
- Distended abdominal veins in which flow is away from the umbilicus (caput medusae)
- Ankle oedema