Christopher Chetsanga
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Christopher J Chetsanga (born 1935 in Murewa, Zimbabwe) is a pre-eminent Zimbabwean scientist.
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[edit] Education
- 1965 obtained a BSc degree at the University of California and Pepperdine University in California, USA[1]
- 1965-1969 obtained MSc and PhD degrees in Biochemistry and Molecular Biology at the University of Toronto, Canada[1]
- 1969-1972 became a Post-doctoral Fellow, Department of Biochemistry and Molecular Biology at Harvard University[2]
[edit] Scientific Achievements
Discovered two enzymes involved in the repair of damaged DNA:
- Formamido-pyrimidine DNA glycosylase that removes damaged 7-methylguanine from DNA (1979).[3]
- DNA cyclase that recloses imidazole rings of guanine and adenine damaged by x-irradiation (1985)[4].
[edit] Work experience
- Assitant Professor, Associate Professor, Full Professor, University of Michigan, 1972-1983
- Professor of Biochemistry, University of Zimbabwe, 1983-1986
- Dean of Science University of Zimbabwe, (1986-1991)
- Pro Vice Chancellor, University of Zimbabwe, (1991-1993)[1]
- Director General, Scientific and Industrial Research and Development Center, Zimbabwe, 1993-2003[2]
[edit] References
- ^ a b c exco5_sc_candidate_shortcv.pdf. Consultive Group on International Agricultural Research. Retrieved on 2008-06-02.
- ^ a b ::SIRDC. www.sirdc.ac.zw. Retrieved on 2008-06-03.
- ^ Chetsanga, C.J.; Lindahl, T. (1979). "Release of 7-methylguanine residues whose imidazole rings have been opened from damaged DNA by a DNA glycosylase from Escherichia coli". Nucleic Acids Res 6 (11): 3673-84. doi:.
- ^ Chetsanga, C.J.; Grigorian, C. (1985). "In situ enzymatic reclosure of opened imidazole rings of purines in DNA damaged by gamma-irradiation.". Proceedings of the National Academy of Sciences of the United States of America 82 (3): 633-637.
