Talk:Cholesterylester transfer protein

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Many professional publications, including the references, refer to this protein as "cholesteryl ester transfer protein", with a space between cholesteryl and ester. Chemically, I suspect it should be one word. Anyone an idea about this? JFW | T@lk 09:46, 20 November 2005 (UTC)

[edit] Should we carry on fiddling with HDL

PMID 17699012 doesn't think so. JFW | T@lk 12:57, 4 November 2007 (UTC)

[edit] Homoexchange purpose?

I find the intro paragraph confusing and don't see explanation in the body of text:

  • What main purpose does CETP serve?
  • What good (to the body) is a homoexchange ("trading a triglyceride for a triglyceride or a cholesteryl ester for a cholesteryl ester") between HDL and VLDL?
  • By the description here, both VLDL and HDL are largely unchanged after CETP does its thing. So how does inhibiting CETP change the level of either?
  • According to the title of the first ref (Zhong S) increasing CETP function increased HDL. So how does torcetrapib lowering CETP increase HDL?

—(updated) David.Throop (talk) 03:58, 18 November 2007 (UTC)

[edit] Useful source

doi:10.1194/jlr.R400007-JLR200 outlines CETP vs atherosclerosis. This predates the torcetratib debacle. JFW | T@lk 23:57, 2 April 2008 (UTC)