Talk:Cholesterylester transfer protein
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Many professional publications, including the references, refer to this protein as "cholesteryl ester transfer protein", with a space between cholesteryl and ester. Chemically, I suspect it should be one word. Anyone an idea about this? JFW | T@lk 09:46, 20 November 2005 (UTC)
[edit] Should we carry on fiddling with HDL
PMID 17699012 doesn't think so. JFW | T@lk 12:57, 4 November 2007 (UTC)
[edit] Homoexchange purpose?
I find the intro paragraph confusing and don't see explanation in the body of text:
- What main purpose does CETP serve?
- What good (to the body) is a homoexchange ("trading a triglyceride for a triglyceride or a cholesteryl ester for a cholesteryl ester") between HDL and VLDL?
- By the description here, both VLDL and HDL are largely unchanged after CETP does its thing. So how does inhibiting CETP change the level of either?
According to the title of the first ref (Zhong S) increasing CETP function increased HDL. So how does torcetrapib lowering CETP increase HDL?
—(updated) David.Throop (talk) 03:58, 18 November 2007 (UTC)
[edit] Useful source
doi:10.1194/jlr.R400007-JLR200 outlines CETP vs atherosclerosis. This predates the torcetratib debacle. JFW | T@lk 23:57, 2 April 2008 (UTC)