Chorioamnionitis

From Wikipedia, the free encyclopedia

Chorioamnionitis Classification and external resources
ICD-10	O41.1, P02.7
ICD-9	658.4, 762.7
eMedicine	ped/89

Chorioamnionitis is an inflammatory condition of pregnancy affecting the uterus. According to a 2000 report by Dr Yvonne W. Wu, a pediatric neurologist at the University of California in San Francisco, chorioamnionitis is a risk factor for periventricular leukomalacia and cerebral palsy in newborns.^[1]

The amniotic sac consists of two membranes:

• The outer membrane, the chorion, contains the amnion and is part of the placenta.
• The inner membrane, the amnion, contains the amniotic fluid and the fetus.

Chorioamnionitis is an inflammation of the chorion and amnion. It is usually caused by a bacterial infection.

Diagnosed clinically with the following criteria: Maternal fever and uterine tenderness in the presence of confirmed Premature Rupture of Membranes (PROM) in the absence of a Upper Respiratory Infection (URI) or Urinary Tract Infection (UTI). ^[2]

[edit] See also

• Cerebral palsy

[edit] References

1. ^ Wu YW, Colford JM (2000). "Chorioamnionitis as a risk factor for cerebral palsy: A meta-analysis". JAMA 284 (11): 1417–24. PMID 10989405. 
2. ^ Elmar Peter Sakala, MD, MA, MPH, FACOG. Professor of GYNOB, Loma Linda University of medicine, California. Codirector of Student Clerkship. Dept of GYNOB

[edit] External links

• OB67 at FPnotebook
• Overview at Cleveland Clinic
• Cerebral palsy inflammation link (29 November 2003) at BBC

v • d • e Pathology of pregnancy, childbirth and the puerperium (O, 630-676) Pregnancy with abortive outcome Ectopic pregnancy - Hydatidiform mole - Miscarriage Oedema, proteinuria and hypertensive disorders Pregnancy-induced hypertension - Pre-eclampsia - Eclampsia - Gestational diabetes Other, predominantly related to pregnancy Hyperemesis gravidarum - Gestational pemphigoid Maternal care related to the fetus and amniotic cavity and possible delivery problems Polyhydramnios - Oligohydramnios - Chorioamnionitis - Premature rupture of membranes - Amniotic band syndrome - Placenta praevia - Braxton Hicks contractions - Antepartum haemorrhage - Placental abruption Complications of labour and delivery Premature birth - Postmature birth - Cephalopelvic disproportion - Dystocia (Shoulder dystocia) - Fetal distress - Vasa praevia - Uterine rupture - hemorrhage - Placenta accreta - Umbilical cord prolapse - Amniotic fluid embolism Maternal complications in the weeks after childbirth Puerperal fever - Peripartum cardiomyopathy - Galactorrhea - Postpartum depression Complications related to the fetus Fetal intervention - Fetal surgery Other Maternal death

v • d • e Certain conditions originating in the perinatal period (P, 760-779) Maternal factors and complications Umbilical cord prolapse - Nuchal cord - Chorioamnionitis Length of gestation and fetal growth Small for gestational age - Large for gestational age - Premature birth - Postmature birth Birth trauma Cephalhematoma - Brachial plexus lesion (Erb's palsy, Klumpke paralysis) Respiratory Intrauterine hypoxia - Infant respiratory distress syndrome - Transient tachypnea of the newborn - Meconium aspiration syndrome - pleural disease (Pneumothorax, Pneumomediastinum) - Wilson-Mikity syndrome - Bronchopulmonary dysplasia Cardiovascular Pneumopericardium - Persistent fetal circulation Haemorrhagic and haematological/ hematologic disease Haemorrhagic disease of the newborn - Hemolytic disease of the newborn - Rh disease - Hydrops fetalis - Hyperbilirubinemia (Kernicterus, Neonatal jaundice) Digestive system Ileus - Necrotizing enterocolitis Integument and temperature regulation Erythema toxicum Other disorders Periventricular leukomalacia - Gray baby syndrome - muscle tone (Congenital hypertonia, Congenital hypotonia) - Congenital rubella syndrome