Chloride peroxidase

From Wikipedia, the free encyclopedia

In enzymology, a chloride peroxidase (EC 1.11.1.10) is an enzyme that catalyzes the chemical reaction

2 RH + 2 Cl- + H₂O₂ $\rightleftharpoons$ 2 RCl + 2 H₂O

The 3 substrates of this enzyme are RH, Cl⁻, and H₂O₂, whereas its two products are RCl and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a peroxide as acceptor (peroxidases). The systematic name of this enzyme class is chloride:hydrogen-peroxide oxidoreductase. This enzyme is also called chloroperoxidase. It employs one cofactor, heme.

1 Structural studies
2 References
3 External links
- 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 30 structures have been solved for this class of enzymes, with PDB accession codes 1A7U, 1A88, 1A8Q, 1A8S, 1A8U, 1BRT, 1CPO, 1IDQ, 1IDU, 1QHB, 1QI9, 1VNC, 1VNE, 1VNF, 1VNG, 1VNH, 1VNI, 1VNS, 2CIV, 2CIW, 2CIX, 2CIY, 2CIZ, 2CJ0, 2CJ1, 2CJ2, 2CPO, 2J18, 2J19, and 2J5M.

[edit] References

IUBMB entry for 1.11.1.10
BRENDA references for 1.11.1.10 (Recommended.)
PubMed references for 1.11.1.10
PubMed Central references for 1.11.1.10
Google Scholar references for 1.11.1.10
Hager LP, Hollenberg PF, Rand-Meir T, Chiang R, Doubek D (1975). "Chemistry of peroxidase intermediates". Ann. N. Y. Acad. Sci. 244: 80–93. doi:10.1111/j.1749-6632.1975.tb41524.x. PMID 1056179.
Morris DR, Hager LP (1966). "Chloroperoxidase. I. Isolation and properties of the crystalline glycoprotein". J. Biol. Chem. 241: 1763–8. PMID 5949836.
Theiler R, Cook JC, Hager LP and Siuda JF (1978). "Halohydrocarbon synthesis by homoperoxidase". Science 202: 1094–1096. doi:10.1126/science.202.4372.1094.