Chenodeoxycholoyltaurine hydrolase

From Wikipedia, the free encyclopedia

In enzymology, a chenodeoxycholoyltaurine hydrolase (EC 3.5.1.74) is an enzyme that catalyzes the chemical reaction

chenodeoxycholoyltaurine + H₂O chenodeoxycholate + taurine

Thus, the two substrates of this enzyme are chenodeoxycholoyltaurine and H₂O, whereas its two products are chenodeoxycholate and taurine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is chenodeoxycholoyltaurine amidohydrolase. This enzyme participates in bile acid biosynthesis.

[edit] References

• IUBMB entry for 3.5.1.74
• BRENDA references for 3.5.1.74 (Recommended.)
• PubMed references for 3.5.1.74
• PubMed Central references for 3.5.1.74
• Google Scholar references for 3.5.1.74
• Kawamoto K, Horibe I, Uchida K (Tokyo). "Purification and characterization of a new hydrolase for conjugated bile acids, chenodeoxycholyltaurine hydrolase, from Bacteroides vulgatus". J. Biochem.: 1049–53. PMID 2628421. 

[edit] External links

The CAS registry number for this enzyme class is 125752-75-2.

• IUBMB entry for 3.5.1.74

• KEGG entry for 3.5.1.74

• BRENDA entry for 3.5.1.74

• NiceZyme view of 3.5.1.74

• EC2PDB: PDB structures for 3.5.1.74

• PRIAM entry for 3.5.1.74

• PUMA2 entry for 3.5.1.74

• IntEnz: Integrated Enzyme entry for 3.5.1.74

• MetaCyc entry for 3.5.1.74

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047742: chenodeoxycholoyltaurine hydrolase

• AMIGO entry for GO code 0047742: chenodeoxycholoyltaurine hydrolase