CHD5

From Wikipedia, the free encyclopedia

Chromodomain helicase DNA binding protein 5

PDB rendering based on 1mm2.

Available structures: 1mm2

Identifiers

Symbol(s)

CHD5; DKFZp434N231; KIAA0444

External IDs

OMIM: 610771 MGI: 3036258 HomoloGene: 56712

Gene ontology
Molecular Function:	• nucleotide binding • DNA binding • chromatin binding • helicase activity • protein binding • ATP binding • ATP-dependent helicase activity • zinc ion binding • hydrolase activity • metal ion binding
Cellular Component:	• chromatin • nucleus
Biological Process:	• chromatin assembly or disassembly • chromatin remodeling • transcription • regulation of transcription, DNA-dependent • nervous system development • chromatin modification

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_015557 (mRNA)
NP_056372 (protein)

XM_902432 (mRNA)
XP_907525 (protein)

Location

Chr 1: 6.08 - 6.16 Mb

n/a

Pubmed search

[1]

[2]

Chromodomain helicase DNA binding protein 5, also known as CHD5, is a human gene.^[1]

[edit] References

^ Entrez Gene: CHD5 chromodomain helicase DNA binding protein 5.

[edit] Further reading

Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.". DNA Res. 9 (3): 99–106. PMID 12168954.
Seki N, Ohira M, Nagase T, et al. (1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.". DNA Res. 4 (5): 345–9. PMID 9455484.
Nagase T, Kikuno R, Ishikawa KI, et al. (2000). "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (1): 65–73. PMID 10718198.
Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20.". Nature 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
Schuster EF, Stöger R (2002). "CHD5 defines a new subfamily of chromodomain-SWI2/SNF2-like helicases.". Mamm. Genome 13 (2): 117–9. doi:10.1007/s00335-001-3042-6. PMID 11889561.
Thompson PM, Gotoh T, Kok M, et al. (2003). "CHD5, a new member of the chromodomain gene family, is preferentially expressed in the nervous system.". Oncogene 22 (7): 1002–11. doi:10.1038/sj.onc.1206211. PMID 12592387.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Bagchi A, Papazoglu C, Wu Y, et al. (2007). "CHD5 is a tumor suppressor at human 1p36.". Cell 128 (3): 459–75. doi:10.1016/j.cell.2006.11.052. PMID 17289567.