Charles A. Dinarello

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Charles A. Dinarello is a professor of medicine currently at the University of Colorado at Denver. He is an expert on inflammatory cytokines, specifically Interleukin 1. Dinarello is considered one of the founding fathers of cytokines having purified and cloned interleukin-1. This important step established the validation of cytokines as mediators of disease, particularly of inflammation. Current studies blocking IL-1 in humans supports Dinarello's and his co-workers pivotal contributions to cytokine biology and the pathogenesis of inflammatory diseases.