Talk:Cerebrospinal fluid
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[edit] How does CSF disseminate?
like where does it go? does it dry like he said? or leak out of our bodies? or do tiny aliens siphon it from our brains? just wondering really. Thejakeman 04:01, 17 January 2007 (UTC)
Huh?... this is somewhat confusing and I suspect incorrect -
CSF returns to the vascular system primarily along the olfactory tracts and into the lymphatic channels of the nasal mucosa. CSF also drains along cranial and spinal nerve roots. At high intercranial pressures CSF flows into the venous system by the arachnoid granulations. [1]
According to my copy of Moore, CSF enters the venous sytem by moving through the arachnoid granulations into the dural sinuses (eg the sup. sag. sinus) Ezuku 14:52, 30 April 2007 (UTC)
"CSF movement allows arterial expansion and contraction by acting like a spring, which prevents wide changes in intracranial blood flow." ...HUH?! Can someone explain this statement? Liquids are not very compressible. I am curious about the various effects of CSF flow, with repect to research in craniosacral therapy. Paul@svacina.com (www.svacina.com)
I think what this person means (or at least what they should mean) is CSF pressure, not flow. Basicly as CSF pressure increases, cerebral blood flow will decrease (or a higher cerebral profusion pressure (= mean arterial pressure - intracranial pressure) will be needed to maintain the current flow).
Has anyone seen any reliable reaserch about the interelationship of mind-altering drugs and the flow of CSF fluid? I have also heard that the drying up of the CSF liquid is what ultimately causes the deterioration of the body in old age, and that certain inhalents might be able to reverse or slow that process. I think there is a lot of very exciting work that can be done in this area, and I was wondering if there is any underway.
[edit] I thought spinal fluid was final...
Well it says in the article it is produced "500 ml/day" then how is it final and won't come back please someone explain to me this does your body always keep making spinal fluid or is it final you lose it it's gone forever?
Please answer! —Preceding unsigned comment added by 76.118.107.105 (talk) 00:18, 27 January 2008 (UTC)
- I'm not sure what you mean by "final". CSF is produced at the rate you mentioned but resorbed at the same rate. There is therefore an equilibrium, unless of course these is a discrepancy between the rates. Removing CSF by lumbar puncture is therefore not a disaster - when the headache is gone the body has already produced more CSF to replace whatever was removed. JFW | T@lk 14:42, 31 January 2008 (UTC)
[edit] Guideline
The ESFN has produced a guideline on "routine" CSF analysis. doi:10.1111/j.1468-1331.2006.01493.x (free too). JFW | T@lk 14:42, 31 January 2008 (UTC)
[edit] Glucose vs lactate
Why is there so much more lactate in CSF? Know it's elementary, but maybe it's worth mentioning. I found a use for it, but I can't reason my way out of it. What pathologies are related to excessive lactate in CSF? Madskile (talk) 16:38, 4 June 2008 (UTC)
