CENTG2

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Centaurin, gamma 2
Identifiers
Symbol(s) CENTG2; AGAP1; GGAP1; KIAA1099; MGC71657
External IDs OMIM: 608651 MGI: 2653690 HomoloGene: 56689
Orthologs
Human Mouse
Entrez 116987 347722
Ensembl ENSG00000157985 ENSMUSG00000055013
Uniprot Q9UPQ3 Q8BXK8
Refseq NM_001037131 (mRNA)
NP_001032208 (protein)		 NM_001037136 (mRNA)
NP_001032213 (protein)
Location Chr 2: 236.07 - 236.7 Mb Chr 1: 91.29 - 91.73 Mb
Pubmed search [1] [2]

Centaurin, gamma 2, also known as CENTG2, is a human gene.[1]

CENTG2 belongs to an ADP-ribosylation factor GTPase-activating (ARF-GAP) protein family involved in membrane traffic and actin cytoskeleton dynamics (Nie et al., 2002).[supplied by OMIM][1]

[edit] References

  1. ^ a b Entrez Gene: CENTG2 centaurin, gamma 2.

[edit] Further reading

  • Kikuno R, Nagase T, Ishikawa K, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 6 (3): 197–205. PMID 10470851. 
  • Nie Z, Stanley KT, Stauffer S, et al. (2003). "AGAP1, an endosome-associated, phosphoinositide-dependent ADP-ribosylation factor GTPase-activating protein that affects actin cytoskeleton.". J. Biol. Chem. 277 (50): 48965–75. doi:10.1074/jbc.M202969200. PMID 12388557. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Xia C, Ma W, Stafford LJ, et al. (2003). "GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.". Mol. Cell. Biol. 23 (7): 2476–88. PMID 12640130. 
  • Nie Z, Boehm M, Boja ES, et al. (2003). "Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1.". Dev. Cell 5 (3): 513–21. PMID 12967569. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Meurer S, Pioch S, Wagner K, et al. (2005). "AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.". J. Biol. Chem. 279 (47): 49346–54. doi:10.1074/jbc.M410565200. PMID 15381706. 
  • Wassink TH, Piven J, Vieland VJ, et al. (2005). "Evaluation of the chromosome 2q37.3 gene CENTG2 as an autism susceptibility gene.". Am. J. Med. Genet. B Neuropsychiatr. Genet. 136 (1): 36–44. doi:10.1002/ajmg.b.30180. PMID 15892143. 
  • Nie Z, Fei J, Premont RT, Randazzo PA (2005). "The Arf GAPs AGAP1 and AGAP2 distinguish between the adaptor protein complexes AP-1 and AP-3.". J. Cell. Sci. 118 (Pt 15): 3555–66. doi:10.1242/jcs.02486. PMID 16079295. 
  • Oh JH, Yang JO, Hahn Y, et al. (2006). "Transcriptome analysis of human gastric cancer.". Mamm. Genome 16 (12): 942–54. doi:10.1007/s00335-005-0075-2. PMID 16341674. 
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