Talk:Cell penetrating peptide

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Paragraph 1: This needs some serious work and I don't have the time to tackle it. The second study was done by Frankel, not Franklin; Chloroquine is not a CPP; viruses do not take up cell penetrating peptides; the cells were infected by HIV, they were not HIV cells. I'm not going to go get the references today and try to fix this. Good luck.

Paragraph 2: I am removing the following part of the discussion of the Abes et al. 2007 paper: The study done by Montpellier 2 also studied the effect of drugs that inhibited binding to the cytosol, to block protein synthesis, and the nucleus inhibiting mRNA synthesis. By measuring the levels of luminenesce they were able to see that reaching the cyotosol and binding to the nucleus are nessacary to the function the CPPs because when inhibited uptake stopped uptake of material or lowered the level significantly.

This needs work if it is to be reinserted. "binding to the cytosol" does not make sense, I assume they mean binding to the cell membrane. There were some nice inhibitor studies in the paper but they need to be accurately reported for inclusion here.

JonMoulton 22:19, 16 May 2007 (UTC)