Cellobiose phosphorylase

From Wikipedia, the free encyclopedia

In enzymology, a cellobiose phosphorylase (EC 2.4.1.20) is an enzyme that catalyzes the chemical reaction

cellobiose + phosphate alpha-D-glucose 1-phosphate + D-glucose

Thus, the two substrates of this enzyme are cellobiose and phosphate, whereas its two products are alpha-D-glucose 1-phosphate and D-glucose.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is cellobiose:phosphate alpha-D-glucosyltransferase. This enzyme participates in starch and sucrose metabolism.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2006, two structures have been solved for this class of enzymes, with PDB accession codes 2CQS and 2CQT.

[edit] References

• IUBMB entry for 2.4.1.20
• BRENDA references for 2.4.1.20 (Recommended.)
• PubMed references for 2.4.1.20
• PubMed Central references for 2.4.1.20
• Google Scholar references for 2.4.1.20
• Alexander JK (1968). "Purification and specificity of cellobiose phosphorylase from Clostridium thermocellum". J. Biol. Chem. 243: 2899–904. PMID 5653182. 
• AYERS WA (1959). "Phosphorolysis and synthesis of cellobiose by cell extracts from Ruminococcus flavefaciens". J. Biol. Chem. 234: 2819–22. PMID 13795349. 

[edit] External links

The CAS registry number for this enzyme class is 9030-20-0.

• IUBMB entry for 2.4.1.20

• KEGG entry for 2.4.1.20

• BRENDA entry for 2.4.1.20

• NiceZyme view of 2.4.1.20

• EC2PDB: PDB structures for 2.4.1.20

• PRIAM entry for 2.4.1.20

• PUMA2 entry for 2.4.1.20

• IntEnz: Integrated Enzyme entry for 2.4.1.20

• MetaCyc entry for 2.4.1.20

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047738: cellobiose phosphorylase

• AMIGO entry for GO code 0047738: cellobiose phosphorylase