CD52
From Wikipedia, the free encyclopedia
CD52 molecule
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Identifiers | |
Symbol | CD52 |
Alt. Symbols | CDW52 |
Entrez | 1043 |
HUGO | 1804 |
OMIM | 114280 |
RefSeq | NM_001803 |
UniProt | P31358 |
Other data | |
Locus | Chr. 1 p36 |
CD52 is a protein present on the surface of mature lymphocytes, but not on the stem cells from which these lymphocytes were derived. It is a glycosylphosphatidylinositol (GPI)--anchored antigen expressed on the all lymphocytes as well as within the male genital tract.
It is the protein targeted by Alemtuzumab.
It is associated with certain types of lymphoma.[1]
[edit] References
- ^ Piccaluga PP, Agostinelli C, Righi S, Zinzani PL, Pileri SA (2007). "Expression of CD52 in peripheral T-cell lymphoma". Haematologica 92 (4): 566–7. PMID 17488672.