Talk:CD36
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This article may be too technical for a general audience. Please help improve this article by providing more context and better explanations of technical details to make it more accessible, without removing technical details. |
[edit] Original research
This is a very technical article with no references. It looks like it is either a copyright violation (it was uploaded anonymously), but I can find no matching source documents (there are copyright violatins the other way!), or it would seem to me to be an original paper. --David Woolley 11:01, 12 November 2005 (UTC)
At least one academic article (full text here) seems to back up what the article indicates. It is not my field of expertise, however, so I can't say much beyond that. --Hansnesse 21:16, 4 January 2006 (UTC)
Most of this is drawn from published work which is in the public domain. I will be adding references where appropriate as fast as i can. V-man 06:17, 7 January 2006 (UTC)
[edit] Cleanup
As well as no references, there are no subpheadings. --David Woolley 11:01, 12 November 2005 (UTC)
Working on a cleanup now. Stay tuned.V-man 06:18, 7 January 2006 (UTC)
[edit] CD36 expression
According to my knowledge, CD36 is not expressed on adult erythrocytes, as is mentioned in the article. It is however expressed on adult erythroid cells as they differentiate from mature BFU-E to reticulocytes [1,2] (and probably on 10-20% of fetal erythrocytes [1]).
Literature:
1. Edelman, P, et al., A monoclonal antibody against an erythrocyte ontogenic antigen identifies fetal and adult erythroid progenitors. Blood, 1986. 67(1): p. 56-63. Link: http://www.bloodjournal.org/content/vol67/issue1/ or http://www.bloodjournal.org/cgi/reprint/67/1/56
2. Greenwalt, D.E., et al., Membrane Glycoprotein-Cd36 - a Review of Its Roles in Adherence, Signal Transduction, and Transfusion Medicine. Blood, 1992. 80(5): p. 1105-1115.
Link: http://www.bloodjournal.org/content/vol80/issue5/ or http://www.bloodjournal.org/cgi/reprint/80/5/1105
--Danielremmers 13:49, 8 February 2006 (UTC)
- Those are some spcific but older references. They seem to contradict the malaria literature. I.E. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2473841&query_hl=14&itool=pubmed_docsumV-man 21:41, 25 February 2006 (UTC)
