Cd2+-exporting ATPase

From Wikipedia, the free encyclopedia

In enzymology, a Cd2+-exporting ATPase (EC 3.6.3.3) is an enzyme that catalyzes the chemical reaction

ATP + H₂O + Cd₂+in ADP + phosphate + Cd₂+out

The 3 substrates of this enzyme are ATP, H₂O, and Cd2+, whereas its 3 products are ADP, phosphate, and Cd2+.

This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (Cd2+-exporting).

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1MWY, 1MWZ, 2AJ0, and 2AJ1.

[edit] References

• IUBMB entry for 3.6.3.3
• BRENDA references for 3.6.3.3 (Recommended.)
• PubMed references for 3.6.3.3
• PubMed Central references for 3.6.3.3
• Google Scholar references for 3.6.3.3
• Silver S, Ji G (1994). "Newer systems for bacterial resistances to toxic heavy metals". Environ. Health. Perspect. 102 Suppl 3: 107–13. PMID 7843081. 
• Tsai KJ, Linet AL (1993). "Formation of a phosphorylated enzyme intermediate by the cadA Cd(2+)-ATPase". Arch. Biochem. Biophys. 305: 267–70. doi:10.1006/abbi.1993.1421. PMID 8373163. 

[edit] External links

• IUBMB entry for 3.6.3.3

• KEGG entry for 3.6.3.3

• BRENDA entry for 3.6.3.3

• NiceZyme view of 3.6.3.3

• EC2PDB: PDB structures for 3.6.3.3

• PRIAM entry for 3.6.3.3

• PUMA2 entry for 3.6.3.3

• IntEnz: Integrated Enzyme entry for 3.6.3.3

• MetaCyc entry for 3.6.3.3

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0008551: cadmium-exporting ATPase

• AMIGO entry for GO code 0008551: cadmium-exporting ATPase