CD120

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Signaling pathway of TNF-R1. Dashed grey lines represent multiple steps
Signaling pathway of TNF-R1. Dashed grey lines represent multiple steps
Identifiers
Symbol TNFRSF1A
Alt. Symbols CD120a, TNFR1
Entrez 7132
HUGO 11916
OMIM 191190
RefSeq NM_001065
UniProt P19438
Other data
Locus Chr. 12 p13.2
Identifiers
Symbol TNFRSF1B
Alt. Symbols CD120a, TNFR2
Entrez 7133
HUGO 11917
OMIM 191191
RefSeq NM_001066
UniProt P20333
Other data
Locus Chr. 1 p36.22

CD120 (Cluster of Differentiation 120), also known as the tumor necrosis factor receptor (TNFR). This protein is a member of the tumor necrosis factor receptor superfamily.[1][2]

Contents

[edit] Receptor subtypes

There are two variants of the receptor, each encoded by a separate gene:

[edit] See also

[edit] References

  1. ^ Locksley RM, Killeen N, Lenardo MJ (2001). "The TNF and TNF receptor superfamilies: integrating mammalian biology". Cell 104 (4): 487–501. doi:10.1016/S0092-8674(01)00237-9. PMID 11239407. 
  2. ^ Hehlgans T, Pfeffer K (2005). "The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games". Immunology 115 (1): 1–20. doi:10.1111/j.1365-2567.2005.02143.x. PMID 15819693. 

[edit] External links