CBX8
From Wikipedia, the free encyclopedia
Chromobox homolog 8 (Pc class homolog, Drosophila)
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PDB rendering based on 2dnv. | ||||||||||||||
Available structures: 2dnv | ||||||||||||||
Identifiers | ||||||||||||||
Symbol(s) | CBX8; PC3; HPC3; RC1 | |||||||||||||
External IDs | MGI: 1353589 HomoloGene: 32199 | |||||||||||||
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RNA expression pattern | ||||||||||||||
Orthologs | ||||||||||||||
Human | Mouse | |||||||||||||
Entrez | 57332 | 30951 | ||||||||||||
Ensembl | ENSG00000141570 | ENSMUSG00000025578 | ||||||||||||
Uniprot | Q9HC52 | Q8BPY2 | ||||||||||||
Refseq | NM_020649 (mRNA) NP_065700 (protein) |
NM_013926 (mRNA) NP_038954 (protein) |
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Location | Chr 17: 75.38 - 75.39 Mb | Chr 11: 118.85 - 118.86 Mb | ||||||||||||
Pubmed search | [1] | [2] |
Chromobox homolog 8 (Pc class homolog, Drosophila), also known as CBX8, is a human gene.[1]
[edit] References
[edit] Further reading
- Bárdos JI, Saurin AJ, Tissot C, et al. (2000). "HPC3 is a new human polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties.". J. Biol. Chem. 275 (37): 28785–92. doi: . PMID 10825164.
- García-Cuéllar MP, Zilles O, Schreiner SA, et al. (2001). "The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3.". Oncogene 20 (4): 411–9. doi: . PMID 11313972.
- Hemenway CS, de Erkenez AC, Gould GC (2001). "The polycomb protein MPc3 interacts with AF9, an MLL fusion partner in t(9;11)(p22;q23) acute leukemias.". Oncogene 20 (29): 3798–805. doi: . PMID 11439343.
- Levine SS, Weiss A, Erdjument-Bromage H, et al. (2002). "The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans.". Mol. Cell. Biol. 22 (17): 6070–8. PMID 12167701.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: . PMID 12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi: . PMID 14702039.
- Obuse C, Yang H, Nozaki N, et al. (2004). "Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase.". Genes Cells 9 (2): 105–20. PMID 15009096.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi: . PMID 15489334.
- Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome.". Cell 122 (6): 957–68. doi: . PMID 16169070.
- Dietrich N, Bracken AP, Trinh E, et al. (2007). "Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locus.". EMBO J. 26 (6): 1637–48. doi: . PMID 17332741.