Caspase 5

From Wikipedia, the free encyclopedia

caspase 5, apoptosis-related cysteine peptidase
Identifiers
Symbol	CASP5
Alt. Symbols	ICE(rel)III, ICH3
Entrez	838
HUGO	1506
OMIM	602665
RefSeq	NM_004347
UniProt	P51878
Other data
EC number	3.4.22.58
Locus	Chr. 11 q22.2-q22.3

Caspase 5 is an enzyme that proteolytically cleaves other proteins at an aspartic acid residue, and belongs to a family of cysteine proteases called caspases. It is an inflammatory caspase, along with caspase 1, caspase 4 and the murine caspase 4 homolog caspase 11, and has a role in the immune system.^[1]

[edit] References

1. ^ Martinon F, Tschopp J (2007). "Inflammatory caspases and inflammasomes: master switches of inflammation". Cell Death Differ. 14 (1): 10–22. doi:10.1038/sj.cdd.4402038. PMID 16977329. 

v • d • e Proteases: cysteine proteases (EC 3.4.22) Caspase Caspase 1 - Caspase 2 - Caspase 3 - Caspase 4 - Caspase 5 - Caspase 8 - Caspase 9 - Caspase 10 - Caspase 12 - Caspase 13 Fruit-derived Papain - Ficain - Bromelain - Actinidain Other Clostripain - Cancer procoagulant - Separase - Calpain - Autophagin