Talk:Cardiac input

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Cardiac input is theory that inverts the [Adolph Fick] solution for [Cardiac Output][Systole]. Systole is about half of the time phase of a single [heartbeat]. Diastole represents the opposed and remaining half of the same heartbeat. Archived and present day European thought suggests [diastole] as a [Windkessel] and contains a vast wealth of understanding of the exchanged compliance of the peripheral vascular and pulmonary beds. Other theories regarding diastole are considered as left sided determination of flow across the mitral valve, split into two time phases, [E wave][Early filling phase] in health representing 70-80% and [A wave][Late filling phase] in health 20-30%. Decline in E:A ratio is well understood as incrementally compromised LV performance. Echocardiographically proven and disclosed theory well describes performance of the left ventricle [LV]. LVEF remains a substantial but quartered determinant of CO and global performance. Contemporary volumetric theory echocardiographically well described for many years by many authors lends itself to [Ejection Fraction] or [EF]. EF remains an expedient, inexpensive and noninvasive determinant of systolic heart function readily applied to every day clinical practice. EF is now being examined as right/pulmonary and left/systemic determinants, and may be further studied as LVEF + RVEF = EF. Posit that an EF over 65% indicates a stiff, noncompliant myocardium. Posit degradation of compliance leads to negative inotropic remodeling of the myocardium. Inversion of Fick for diastole remains to be investigated. The [Guyton][sump] model opposed to a systolic [Adolph Fick][pump] is perhaps the first historical mention of the abstract notion of diastole. [Guyton]s' sump and [Windkessel] physiology strongly suggest that diastole is not a passive /relaxation phase. Injection Fraction [IF] is posited as an indicator of diastolic definition to the extent that Ejection Fraction [EF] is posited as an equivalent of definition systole. Given EF=ESV/EDV, would the inversion to solve for diastole be IF=EDV/ESV? If so, this could represent promise in further useful noninvasive, inexpensive clinical data regarding diastolic heart failure.--Lbeben (talk) 04:10, 7 June 2008 (UTC)