Carnitine 3-dehydrogenase

From Wikipedia, the free encyclopedia

In enzymology, a carnitine 3-dehydrogenase (EC 1.1.1.108) is an enzyme that catalyzes the chemical reaction

carnitine + NAD⁺ 3-dehydrocarnitine + NADH + H⁺

Thus, the two substrates of this enzyme are carnitine and NAD⁺, whereas its 3 products are 3-dehydrocarnitine, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is carnitine:NAD+ 3-oxidoreductase.

[edit] References

• IUBMB entry for 1.1.1.108
• BRENDA references for 1.1.1.108 (Recommended.)
• PubMed references for 1.1.1.108
• PubMed Central references for 1.1.1.108
• Google Scholar references for 1.1.1.108
• Aurich H, Kleber HP, Sorger H, Tauchert H (1968). "[Purification and properties of carnitine dehydrogenase from Pseudomonas aeruginosa]". Eur. J. Biochem. 6: 196–201. PMID 4302217. 
• Schopp W, Sorger H, Kleber HP, Aurich H (1969). "[Kinetic studies of the reaction mechanism of carnitine dehydrogenase of Pseudomonas aeruginosa]". Eur. J. Biochem. 10: 56–60. PMID 4310279. 

[edit] External links

The CAS registry number for this enzyme class is 9045-45-8.

• IUBMB entry for 1.1.1.108

• KEGG entry for 1.1.1.108

• BRENDA entry for 1.1.1.108

• NiceZyme view of 1.1.1.108

• EC2PDB: PDB structures for 1.1.1.108

• PRIAM entry for 1.1.1.108

• PUMA2 entry for 1.1.1.108

• IntEnz: Integrated Enzyme entry for 1.1.1.108

• MetaCyc entry for 1.1.1.108

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047728: carnitine 3-dehydrogenase

• AMIGO entry for GO code 0047728: carnitine 3-dehydrogenase