Carboxymethylhydantoinase

From Wikipedia, the free encyclopedia

In enzymology, a carboxymethylhydantoinase (EC 3.5.2.4) is an enzyme that catalyzes the chemical reaction

L-5-carboxymethylhydantoin + H₂O N-carbamoyl-L-aspartate

Thus, the two substrates of this enzyme are L-5-carboxymethylhydantoin and H₂O, whereas its product is N-carbamoyl-L-aspartate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. The systematic name of this enzyme class is L-5-carboxymethylhydantoin amidohydrolase. This enzyme is also called hydantoin hydrolase.

[edit] References

• IUBMB entry for 3.5.2.4
• BRENDA references for 3.5.2.4 (Recommended.)
• PubMed references for 3.5.2.4
• PubMed Central references for 3.5.2.4
• Google Scholar references for 3.5.2.4
• LIEBERMAN I, KORNBERG A (1954). "Enzymatic synthesis and breakdown of a pyrimidine, orotic acid. I Dihydroortic acid, ureidosuccinic acid, and 5-carboxymethylhydantoin". J. Biol. Chem. 207: 911–24. PMID 13163076. 

[edit] External links

The CAS registry number for this enzyme class is 9025-14-3.

• IUBMB entry for 3.5.2.4

• KEGG entry for 3.5.2.4

• BRENDA entry for 3.5.2.4

• NiceZyme view of 3.5.2.4

• EC2PDB: PDB structures for 3.5.2.4

• PRIAM entry for 3.5.2.4

• PUMA2 entry for 3.5.2.4

• IntEnz: Integrated Enzyme entry for 3.5.2.4

• MetaCyc entry for 3.5.2.4

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047771: carboxymethylhydantoinase

• AMIGO entry for GO code 0047771: carboxymethylhydantoinase