Carbon-monoxide dehydrogenase (ferredoxin)

From Wikipedia, the free encyclopedia

In enzymology, a carbon-monoxide dehydrogenase (ferredoxin) (EC 1.2.7.4) is an enzyme that catalyzes the chemical reaction

CO + H₂O + oxidized ferredoxin CO₂ + reduced ferredoxin

The 3 substrates of this enzyme are CO, H₂O, and oxidized ferredoxin, whereas its two products are CO₂ and reduced ferredoxin.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is carbon-monoxide,water:ferredoxin oxidoreductase.

[edit] References

• IUBMB entry for 1.2.7.4
• BRENDA references for 1.2.7.4 (Recommended.)
• PubMed references for 1.2.7.4
• PubMed Central references for 1.2.7.4
• Google Scholar references for 1.2.7.4
• Meyer O, Schlegel HG (1980). "Carbon monoxide:methylene blue oxidoreductase from Pseudomonas carboxydovorans". J. Bacteriol. 141: 74–80. PMID 7354006. 
• Ragsdale SW, Clark JE, Ljungdahl LG, Lundie LL, Drake HL (1983). "Properties of purified carbon monoxide dehydrogenase from Clostridium thermoaceticum, a nickel, iron-sulfur protein". J. Biol. Chem. 258: 2364–9. PMID 6687389. 
• Doukov TI, Iverson TM, Seravalli J, Ragsdale SW, Drennan CL (2002). "A Ni-Fe-Cu center in a bifunctional carbon monoxide dehydrogenase/acetyl-CoA synthase". Science. 298: 567–72. doi:10.1126/science.1075843. PMID 12386327. 

[edit] External links

• IUBMB entry for 1.2.7.4

• KEGG entry for 1.2.7.4

• BRENDA entry for 1.2.7.4

• NiceZyme view of 1.2.7.4

• EC2PDB: PDB structures for 1.2.7.4

• PRIAM entry for 1.2.7.4

• PUMA2 entry for 1.2.7.4

• IntEnz: Integrated Enzyme entry for 1.2.7.4

• MetaCyc entry for 1.2.7.4

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0043885: carbon-monoxide dehydrogenase (ferredoxin)

• AMIGO entry for GO code 0043885: carbon-monoxide dehydrogenase (ferredoxin)