Carbetocin


Carbetocin
Systematic (IUPAC) name
(2S)-1-[(3S,6S,9S,12S,15S)-12-[(2S)-butan-2-yl]- 9-(2-carbamoylethyl)-6-(carbamoylmethyl)-15- [(4-hydroxyphenyl)methyl]-16-methyl-5,8,11,14,17- pentaoxo-1-thia-4,7,10,13,16-pentazacycloicosane- 3-carbonyl]-N-[(1S)-1-(carbamoylmethylcarbamoyl)- 3-methyl-butyl]pyrrolidine-2-carboxamide
Identifiers
CAS number	37025-55-1
ATC code	H01BB03
PubChem	71715
Chemical data
Formula	C₄₅H₆₉N₁₁O₁₂S
Mol. mass	988.162 g/mol
Pharmacokinetic data
Bioavailability	80% (IM)
Metabolism	?
Half life	40 minutes
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status	POM(UK) Not available (U.S.)
Routes	Intravenous, intramuscular

Carbetocin (INN) is a drug used to control postpartum hemorrhage, bleeding after giving birth. It is sold under the trade name Duratocin. It is an analogue of oxytocin, and its action is similar to that of oxytocin; it causes contraction of the uterus.

Carbetocin is available in Canada and the United Kingdom, but not in the United States.

[edit] See also

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v • d • e Pituitary and hypothalamic hormones and analogues (H01)

Anterior pituitary	Adrenocorticotropic hormone (Corticotropin, Tetracosactide) - Thyrotropin - Somatropin/agonists (Somatrem, Mecasermin, Sermorelin) - other (Pegvisomant)

Posterior pituitary	Vasopressin (Desmopressin, Lypressin, Terlipressin, Ornipressin, Argipressin) - Oxytocin (Demoxytocin, Carbetocin)

Hypothalamic	gonadotropin-releasing hormones (Gonadorelin, Nafarelin, Histrelin) - antigrowth hormone (Somatostatin, Octreotide, Lanreotide) - anti-gonadotropin-releasing hormones (Ganirelix, Cetrorelix)