Canine minute virus
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| Canine minute virus | ||||||||
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 EM of canine parvovirus
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Canine minute virus is a type of virus of the family Parvoviridae that infects dogs. It is most similar to bovine parvovirus in its protein structure and DNA.[1] A virus causing respiratory disease in humans has been called human bocavirus due to its similarity to both these viruses (bovine canine virus).[2] Canine minute virus was originally discovered in Germany in 1967 in military dogs,[3] although it was originally thought to not cause disease. Dogs and puppies are infected orally, and the virus is spread transplacentally to the fetuses. Symptoms are seen most commonly between the ages of one to three weeks[3] and include severe diarrhea, difficulty breathing, and anorexia. In severe cases it is fatal.
In experimental infections, the virus is spread transplacentally when the dam (mother) is infected between 25 and 30 days of gestation and can result in abortion. When the dam is infected between 30 and 35 days, the puppies were sometimes born with myocarditis and anasarca.[3] Pathological lesions in fetuses in experimental infections were found in the lung and small intestine.[4]
[edit] References
- ^ Schwartz D, Green B, Carmichael L, Parrish C (2002). "The canine minute virus (minute virus of canines) is a distinct parvovirus that is most similar to bovine parvovirus". Virology 302 (2): 219–23. doi:. PMID 12441065.
- ^ McIntosh K (2006). "Human bocavirus: developing evidence for pathogenicity". J Infect Dis 194 (9): 1197–9. doi:. PMID 17041844.
- ^ a b c Carmichael, L. (2004). Neonatal Viral Infections of Pups: Canine Herpesvirus and Minute Virus of Canines (Canine Parvovirus-1). Recent Advances in Canine Infectious Diseases. Retrieved on 2006-06-25.
- ^ Hashimoto A (1999). Canine parvovirus type-1 (MVC): Pathomorphological studies on the experimentally infected fetus and MVC-infected cultured cells. Canine Infectious Diseases: From Clinics to Molecular Pathogenesis. Retrieved on 2007-04-07.
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