Calgranulin

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Calgranulin is an S-100 calcium-binding protein that is expressed in multiple cell types, including renal epithelial cells and neutrophils. Some in vitro evidence suggests that calgranulin can inhibit the precipitation of calcium oxalate in a urine-like environment at calgranulin concentrations below physiological concentrations.^[1] Thus, it may also function in vivo as an inhibitor of calcium oxalate kidney stone formation. However, the role of calgranulin in the stone formation process has not been evaluated.

[edit] Genes

• S100A8, S100A9, S100A12

[edit] References

1. ^ Pillay S, Asplin J, Coe F (1998). "Evidence that calgranulin is produced by kidney cells and is an inhibitor of calcium oxalate crystallization". Am J Physiol 275 (2 Pt 2): F255–61. PMID 9691016. 

[edit] External links

• MeSH Calgranulin+A
• MeSH Calgranulin+B

v • d • e Surface antigens Histocompatibility/Human leukocyte antigen MHC - MHC class I (HLA-A, HLA-B, HLA-C, HLA-E) MHC class II (HLA-DP, HLA-DQ, HLA-DR) - Minor histocompatibility antigen Other Arrestin - Calgranulin - Blood group antigens - Cell adhesion molecules - Differentiation antigens