Talk:Cadherin
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From the article "Cadherins within one class will only bind to themselves." I think this is untrue in general. Please see Prakasam et al. (2005) PNAS (doi:10.1073/pnas.0606701103). The authors present bead aggregation and force displacement measurements on C-, E-, and N- cadherin from Xenopus, canine, and chicken, respectively. The different forms bind to each other and heterophillic adhesion strength is not significantly different from homophillic adhesion strength.
[edit] Cancer
Should there be something on E-cadherin's significance in breast cancer? See Tan DSP et al. (1999). The biological and prognostic significance of cell polarity and E-cadherin in grade I infiltrating ductal carcinoma of the breast. Journal of Pathology, 189(1), 20-7. —Preceding unsigned comment added by Bondegezou (talk • contribs) 14:59, 5 September 2007 (UTC)
