Cadaverine

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Cadaverine
IUPAC name pentane-1,5-diamine
Identifiers
CAS number [462-94-2]
PubChem 273
MeSH Cadaverine
SMILES NCCCCCN
Properties
Molecular formula C5H14N2
Molar mass 102.178
Density 0.870 g/cm³
Melting point

9 °C

Boiling point

178-180 °C

Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Cadaverine is a foul-smelling molecule produced by protein hydrolysis during putrefaction of animal tissue. Cadaverine is a toxic[1] diamine with the formula NH2(CH2)5NH2, which is similar to putrescine. Cadaverine is also known by the names 1,5-pentanediamine and pentamethylenediamine.

Contents

[edit] Production

Cadaverine is the decarboxylation product of the amino acid lysine.

However, this diamine is not purely associated with putrefaction. It is also produced in small quantities by living beings. It is partially responsible for the distinctive smell of urine and semen.

[edit] Toxicity

Cadaverine is toxic in large doses. In rats it had a low acute oral toxicity of more than 2000 mg/kg body weight[1].

[edit] See also

[edit] Notes

  1. ^ Lewis 1998, Page 212

[edit] References

  • Lewis, Robert Alan (1998). Lewis' Dictionary of Toxicology. CRC Press. ISBN 1566702232.