CAD (gene)
From Wikipedia, the free encyclopedia
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
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Identifiers | |
Symbol | CAD |
Entrez | 790 |
HUGO | 1424 |
OMIM | 114010 |
RefSeq | NM_004341 |
UniProt | P27708 |
Other data | |
EC number | 2.1.3.2 |
Locus | Chr. 2 p21 |
CAD is a gene which encodes several enzymes involved in pyrimidine biosynthesis. De-novo synthesis starts with cytosolic carbamoylphosphate synthetase II which uses glutamine, carbon dioxide and 2 ATP. This enzyme is inhibited by UTP.