C1orf19

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Chromosome 1 open reading frame 19
PDB rendering based on 2gw6.
Available structures: 2gw6
Identifiers
Symbol(s) C1orf19; sen15
External IDs OMIM: 608756 HomoloGene: 12002
Orthologs
Human Mouse
Entrez 116461 n/a
Ensembl ENSG00000198860 n/a
Uniprot Q8WW01 n/a
Refseq NM_052965 (mRNA)
NP_443197 (protein)		 n/a (mRNA)
n/a (protein)
Location Chr 1: 182.29 - 182.31 Mb n/a
Pubmed search [1] n/a

Chromosome 1 open reading frame 19, also known as C1orf19, is a human gene.[1]

tRNA splicing is a fundamental process required for cell growth and division. SEN15 is a subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns, the first step in tRNA splicing (Paushkin et al., 2004).[supplied by OMIM][1]

[edit] References

  1. ^ a b Entrez Gene: C1orf19 chromosome 1 open reading frame 19.

[edit] Further reading

  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMID 15231748. 
  • Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMID 15231747. 
  • Paushkin SV, Patel M, Furia BS, et al. (2004). "Identification of a human endonuclease complex reveals a link between tRNA splicing and pre-mRNA 3' end formation.". Cell 117 (3): 311–21. PMID 15109492. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Sood R, Bonner TI, Makalowska I, et al. (2001). "Cloning and characterization of 13 novel transcripts and the human RGS8 gene from the 1q25 region encompassing the hereditary prostate cancer (HPC1) locus.". Genomics 73 (2): 211–22. doi:10.1006/geno.2001.6500. PMID 11318611. 
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