Butanal dehydrogenase

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In enzymology, a butanal dehydrogenase (EC 1.2.1.57) is an enzyme that catalyzes the chemical reaction

butanal + CoA + NAD(P)+ butanoyl-CoA + NAD(P)H + H⁺

The 4 substrates of this enzyme are butanal, CoA, NAD⁺, and NADP⁺, whereas its 4 products are butanoyl-CoA, NADH, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is butanal:NAD(P)+ oxidoreductase (CoA-acylating). This enzyme participates in butanoate metabolism.

[edit] References

• IUBMB entry for 1.2.1.57
• BRENDA references for 1.2.1.57 (Recommended.)
• PubMed references for 1.2.1.57
• PubMed Central references for 1.2.1.57
• Google Scholar references for 1.2.1.57
• Palosaari NR, Rogers P (1988). "Purification and properties of the inducible coenzyme A-linked butyraldehyde dehydrogenase from Clostridium acetobutylicum". J. Bacteriol. 170: 2971–6. PMID 3384801. 

[edit] External links

The CAS registry number for this enzyme class is 116412-25-0.

• IUBMB entry for 1.2.1.57

• KEGG entry for 1.2.1.57

• BRENDA entry for 1.2.1.57

• NiceZyme view of 1.2.1.57

• EC2PDB: PDB structures for 1.2.1.57

• PRIAM entry for 1.2.1.57

• PUMA2 entry for 1.2.1.57

• IntEnz: Integrated Enzyme entry for 1.2.1.57

• MetaCyc entry for 1.2.1.57

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047759: butanal dehydrogenase

• AMIGO entry for GO code 0047759: butanal dehydrogenase