BTNL2

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Butyrophilin-like 2 (MHC class II associated)
Identifiers
Symbol(s) BTNL2; BTL-II; HSBLMHC1
External IDs OMIM: 606000 MGI: 1859549 HomoloGene: 10482
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 56244 547431
Ensembl ENSG00000204290 ENSMUSG00000024340
Uniprot Q9UIR0 O70355
Refseq NM_019602 (mRNA)
NP_062548 (protein)		 NM_079835 (mRNA)
NP_524574 (protein)
Location Chr 6: 32.47 - 32.48 Mb Chr 17: 33.96 - 33.98 Mb
Pubmed search [1] [2]

Butyrophilin-like 2 (MHC class II associated), also known as BTNL2, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: BTNL2 butyrophilin-like 2 (MHC class II associated).

[edit] Further reading

  • Stammers M, Rowen L, Rhodes D, et al. (2000). "BTL-II: a polymorphic locus with homology to the butyrophilin gene family, located at the border of the major histocompatibility complex class II and class III regions in human and mouse.". Immunogenetics 51 (4-5): 373-82. PMID 10803852. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805-11. doi:10.1038/nature02055. PMID 14574404. 
  • Hiller M, Huse K, Szafranski K, et al. (2005). "Widespread occurrence of alternative splicing at NAGNAG acceptors contributes to proteome plasticity.". Nat. Genet. 36 (12): 1255-7. doi:10.1038/ng1469. PMID 15516930. 
  • Valentonyte R, Hampe J, Huse K, et al. (2005). "Sarcoidosis is associated with a truncating splice site mutation in BTNL2.". Nat. Genet. 37 (4): 357-64. doi:10.1038/ng1519. PMID 15735647. 
  • Rybicki BA, Walewski JL, Maliarik MJ, et al. (2006). "The BTNL2 gene and sarcoidosis susceptibility in African Americans and Whites.". Am. J. Hum. Genet. 77 (3): 491-9. doi:10.1086/444435. PMID 16080124. 
  • Traherne JA, Barcellos LF, Sawcer SJ, et al. (2006). "Association of the truncating splice site mutation in BTNL2 with multiple sclerosis is secondary to HLA-DRB1*15.". Hum. Mol. Genet. 15 (1): 155-61. doi:10.1093/hmg/ddi436. PMID 16321988. 
  • Orozco G, Eerligh P, Sánchez E, et al. (2006). "Analysis of a functional BTNL2 polymorphism in type 1 diabetes, rheumatoid arthritis, and systemic lupus erythematosus.". Hum. Immunol. 66 (12): 1235-41. doi:10.1016/j.humimm.2006.02.003. PMID 16690410. 
  • Campo I, Morbini P, Zorzetto M, et al. (2007). "Expression of receptor for advanced glycation end products in sarcoid granulomas.". Am. J. Respir. Crit. Care Med. 175 (5): 498-506. doi:10.1164/rccm.200601-136OC. PMID 17170388. 
  • Arnett HA, Escobar SS, Gonzalez-Suarez E, et al. (2007). "BTNL2, a butyrophilin/B7-like molecule, is a negative costimulatory molecule modulated in intestinal inflammation.". J. Immunol. 178 (3): 1523-33. PMID 17237401. 
  • Möller M, Kwiatkowski R, Nebel A, et al. (2007). "Allelic variation in BTNL2 and susceptibility to tuberculosis in a South African population.". Microbes Infect. 9 (4): 522-8. doi:10.1016/j.micinf.2007.01.011. PMID 17347014. 
  • Johnson CM, Traherne JA, Jamieson SE, et al. (2007). "Analysis of the BTNL2 truncating splice site mutation in tuberculosis, leprosy and Crohn's disease.". Tissue Antigens 69 (3): 236-41. doi:10.1111/j.1399-0039.2006.00795.x. PMID 17493147. 
  • Mochida A, Kinouchi Y, Negoro K, et al. (2007). "Butyrophilin-like 2 gene is associated with ulcerative colitis in the Japanese under strong linkage disequilibrium with HLA-DRB1*1502.". Tissue Antigens 70 (2): 128-35. doi:10.1111/j.1399-0039.2007.00866.x. PMID 17610417. 
  • Spagnolo P, Sato H, Grutters JC, et al. (2007). "Analysis of BTNL2 genetic polymorphisms in British and Dutch patients with sarcoidosis.". Tissue Antigens 70 (3): 219-27. doi:10.1111/j.1399-0039.2007.00879.x. PMID 17661910. 
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