Brunner's glands

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Brunner's glands
Section of duodenum of cat. (Duodenal glands in submucosa labeled at right, fourth from the top.)
Latin glandulae duodenales
Gray's subject #248 1176
Dorlands/Elsevier g_06/12392383

Brunner glands (or Pancreal glands) are compound tubular submucosal glands found in that portion of the duodenum which is above the sphincter of Oddi. The main function of these glands is to produce an alkaline secretion (containing bicarbonate) in order to:

  • protect the duodenum from the acidic content of chyme (which is introduced into the duodenum from the stomach);
  • provide an alkaline condition for the intestinal enzymes to be active, thus enabling absorption to take place;
  • lubricate the intestinal walls.

They are also the distinguishing feature of the duodenum.

Human brunner's gland
Human brunner's gland


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