Brodimoprim
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Brodimoprim
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Systematic (IUPAC) name | |
5-[(4-bromo-3,5-dimethoxyphenyl)methyl] pyrimidine-2,4-diamine |
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Identifiers | |
CAS number | ? |
ATC code | J01 |
PubChem | |
Chemical data | |
Formula | C13H15BrN4O2 |
Mol. mass | 339.188 g/mol |
Pharmacokinetic data | |
Bioavailability | ? |
Metabolism | ? |
Half life | ? |
Excretion | ? |
Therapeutic considerations | |
Pregnancy cat. |
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Legal status | |
Routes | ? |
Brodimoprim is a structural derivative of trimethoprim. In brodimoprim, the 4-methoxy group of trimethoprim is replaced with a bromine atom.
As trimethoprim, brodimoprim is a selective inhibitor of bacterial dihydrofolate reductase.[1]
[edit] References
- ^ Thomson CJ (1993). "Trimethoprim and brodimoprim resistance of gram-positive and gram-negative bacteria". J Chemother 5 (6): 45864. PMID 8195838.
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