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Newest data suggest that Brefeldin A may not alter the transport from the ER to the Golgi Apparatus but the retrograde transport from the Golgi to the ER in plant cells see:"Reevaluation of the Effects of Brefeldin A on Plant Cells using Tabacco bright yellow 2 cells exprssing golgi-targeted green fluorescent protein and copI antisera" Ritzentaler et.al. 2002
Arf is a GTPase involved in the formation of COPI vesicles, which are involved in retrograde transport and Brefeldin A interacts with Arf.