BPIL1

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Bactericidal/permeability-increasing protein-like 1
Identifiers
Symbol(s) BPIL1; C20orf184; LPLUNC2; RYSR; dJ726C3.2
External IDs MGI: 1913807 HomoloGene: 11884
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 80341 66557
Ensembl ENSG00000078898 ENSMUSG00000027481
Uniprot Q8N4F0 Q14AS4
Refseq NM_025227 (mRNA)
NP_079503 (protein)		 NM_025631 (mRNA)
NP_079907 (protein)
Location Chr 20: 31.06 - 31.08 Mb Chr 2: 153.57 - 153.59 Mb
Pubmed search [1] [2]

Bactericidal/permeability-increasing protein-like 1, also known as BPIL1, is a human gene.[1]

This gene encodes a member of the lipid transfer/lipopolysaccharide binding protein (LT/LBP) gene family. It is highly expressed in hypertrophic tonsils. This gene and three other members of the LT/LBP gene family form a cluster on the long arm of chromosome 20.[1]

[edit] References

  1. ^ a b Entrez Gene: BPIL1 bactericidal/permeability-increasing protein-like 1.

[edit] Further reading

  • Bingle CD, Bingle L (2000). "Characterisation of the human plunc gene, a gene product with an upper airways and nasopharyngeal restricted expression pattern.". Biochim. Biophys. Acta 1493 (3): 363–7. PMID 11018263. 
  • Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20.". Nature 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052. 
  • Bingle CD, Craven CJ (2003). "PLUNC: a novel family of candidate host defence proteins expressed in the upper airways and nasopharynx.". Hum. Mol. Genet. 11 (8): 937–43. PMID 11971875. 
  • Mulero JJ, Boyle BJ, Bradley S, et al. (2002). "Three new human members of the lipid transfer/lipopolysaccharide binding protein family (LT/LBP).". Immunogenetics 54 (5): 293–300. doi:10.1007/s00251-002-0467-3. PMID 12185532. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Andrault JB, Gaillard I, Giorgi D, Rouquier S (2004). "Expansion of the BPI family by duplication on human chromosome 20: characterization of the RY gene cluster in 20q11.21 encoding olfactory transporters/antimicrobial-like peptides.". Genomics 82 (2): 172–84. PMID 12837268. 
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309. 
  • Zhang Z, Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites.". Protein Sci. 13 (10): 2819–24. doi:10.1110/ps.04682504. PMID 15340161. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ramachandran P, Boontheung P, Xie Y, et al. (2006). "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.". J. Proteome Res. 5 (6): 1493–503. doi:10.1021/pr050492k. PMID 16740002. 
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